Product Information
ZincoIsel Sheep is a unique, soluble glass trace element bolus for sheep, which delivers rumen-available ionic zinc, ionic cobalt, iodine and selenium to the animal at a controlled and constant rate for up to four months. ZincoIsel Sheep contains no copper.
ZincoIsel Sheep’s unique soluble glass is designed to dissolve at a controlled rate, meaning there are no peaks or troughs in supplementation.
Uses
For use in areas of zinc, iodine and selenium deficiencies and for the improvement of cobalt supply.
Benefits
Withdrawal Period
Sheep
Meat and Offal: Zero days
Milk: Zero days
https://www.bimeda.ie/media/k2/attachments/1ZIN008_Data_Sheet.pdf
ZINCOISEL DATA
SHEEP Trace element bolus containing zinc, iodine, cobalt and selenium
USES
For use in areas of zinc, iodine and selenium
deficiencies and for the improvement of cobalt supply.
The ZincoIsel sheep bolus supplements the diet of the
sheep with the nutritionally essential minerals zinc,
cobalt, iodine and selenium, and will last over the
grazing season.
Global Excellence in Animal Health
ANALYTICAL CONSTITUENTS
Calcium >2%, Magnesium <1%, Sodium 11%,
Phosphorus 18%
Weight of bolus: 33g
WARNING
Remove bolus from foil and ensure bolus is close to
body temperature at administration.
INCLUSION RATE
Ruminating sheep weighing over 30 kg: 1 bolus may
be given at any convenient time in the sheep
management year. It is particularly appropriate to
give ZincoIsel at, or just before, lambing, to cover
lambing, lactation and the grazing season.
METHOD & ROUTE(S) OF ADMINISTRATION
Take care to read the instructions carefully before
administering the bolus.
Administer orally using an oesophageal balling
applicator, which delivers the bolus directly into the
top of the gullet. Great care should be taken not to
cause any injury by placing the applicator head too
far inside the throat of the animal. Ensure that each
animal has swallowed the bolus by holding the
mouth closed and observing the animal for a short
time after administration. Gentle massage of the
throat may facilitate swallowing of the bolus. To
minimise the risk of regurgitation or injury, avoid
rough handling of animals. Following oral
administration, the bolus lodges in the reticulum
where it dissolves. Boluses are sensitive to sudden
temperature changes such as may occur when very
cold bolus is swallowed by an animal. It is important
that the bolus is close to body temperature at
administration.
TRACE ELEMENT INFORMATION
Zinc deficiency results in reduced growth, reduced
feed intake, loss of hair, skin lesions, excessive
salivation, swollen feet, and impaired reproduction. A
deficiency of zinc in males reduces testicular
development and sperm production. In females,
cycling and conception rates are decreased by zinc
deficiency.
Cobalt is an integral part in Vitamin B12
(cyanocobalamin), which is important for several
metabolic functions. This vitamin is synthesised by
micro-organisms in the rumen and is absorbed from
there into the systemic circulation. Vitamin B12 acts
as a co-enzyme in several metabolic pathways and in
ruminants its main role is in the formation of
propionate, which is required for synthesis of
glucose via succinate in the liver.
Iodine is required for the synthesis of
tri-iodothyronine (T3) and tetra-iodothyronine
(thyroxine T4) in the thyroid gland. These hormones
are derivatives of the amino acid tyrosine. The
function of the iodine hormones is to affect basal
metabolic rate and thus accelerate growth and
increase oxygen consumption. A deficiency of iodine
will result in impaired production of these hormones
and, as a result, goitre (enlarged thyroid gland) can
be seen. The clinical consequences of iodine
deficiency are seen predominantly as reproductive
abnormalities. Note that this condition can also arise
due to selenium deficiency, which can reduce the
conversion of T4 into the active T3 form, and also
due to the consumption of food containing
goitrogens. Goitrogens are substances particularly
found in brassicas (such as kale, cabbage and rape),
which inhibit the iodination of tyrosine and hence
the synthesis of thyroxine.
Selenium is an integral part in the glutathione
peroxidase (GSH-Px) enzymes, which are involved in
the protection from oxidative stress. These enzymes
have a synergistic role with Vitamin E and other
antioxidants in removing toxic peroxides from tissue
and preventing oxidative damage to cell
membranes. Selenium is required in the thyroid
gland for the conversion of T4 to T3, the active
thyroxine molecule as selenium is required in the
iodothyronine deiodinase enzymes.
SPECIAL PRECAUTIONS FOR USE
Protection to operators: to minimise the risk of
contact allergy, wear gloves when handling this
product. Do not administer to non-ruminating sheep.
Do not administer any aids to alter dissolution of the
bolus, (e.g. steel grinders, grub screws etc). Do not
administer selenium by injection while the bolus is
still active unless advised by a veterinary surgeon.
Simultaneous supplementation of nutrients
additives to those incorporated in the bolus should
be avoided. In cases where the trace element status
of the flock is uncertain, it is advisable to seek
veterinary advice. Protective measures to avoid
exposure with Cobalt by inhalation or by dermal
route should be taken.
Warming: Remove boluses from foil pack and ensure
they are at body temperature before administering.
Remove the boluses from all packaging (including
the foil and plastic) and place the boluses inside
clothing pockets close to the body. Never place
boluses in warm or hot water.
The boluses use unique soluble glass technology
which means that they are sensitive to sudden
changes in temperature such as may happen when
very cold boluses are swallowed by the animal.
Failure to ensure the boluses are warmed prior to
administration may result in the development of fine
cracks which can alter the activity of the bolus.
WITHDRAWALS
Milk, meat and offal of the animal can be used
directly after administration.
LEGAL CATEGORY
Complementary dietetic feed
This is not a veterinary medicine which is subject to
authorisation by the HPRA.
SPECIAL STORAGE/DISPOSAL INSTRUCTIONS
Store in a dry place. Do not freeze. Protect from frost.
Once the package has been opened, store unused
boluses in the plastic tray in the original packaging,
in an airtight container. Boluses which become
discoloured or damaged must be discarded. Dispose
of any unused product and empty containers in
accordance with guidance from your local waste
regulation authority. Keep out of reach and sight of
children.
For use in animals only
Before using, it is recommended to have advice from
a Veterinarian or Nutritionist concerning:
1: balance of trace elements in the daily ration
2: trace elements status of flock
MINERAL COMPLEMENTARY FEED
Applicator Instructions
http://www.bimeda.ie/media/k2/attachments/Bimeda_Sheep_Bolus_Administration_Guidelines_2.pdf
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